Medical Center District Vacation Packages
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Top Holiday Package Deals in Medical Center District
Price found within the past 48 hours. Click for updated prices.
InterContinental San Antonio Riverwalk by IHG
Downtown San Antonio
CA $762
per person
Sep 13 - Sep 17
found 13 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to San Antonio (SAT)
9.2/10 Wonderful! (743 reviews)
The stat was everything I needed
Js went out there for a weekend getaway and really enjoyed it.
Reviewed on Aug 10, 2026
Hotel Valencia Riverwalk
Downtown San Antonio
CA $897
per person
Sep 13 - Sep 17
found 13 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to San Antonio (SAT)
9.4/10 Exceptional! (2,963 reviews)
$60 dollar for you valet parking after your booking! Not good .. I will not recommend it. I’d like 4 different businesses in the same building..
Reviewed on Aug 11, 2026
Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown San Antonio
5 out of top 10 points of interest in this area
Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.
Uptown
While visiting Uptown, you might make a stop by sights like Alamo Quarry Market and San Antonio Zoo and Aquarium.
Far West Side
1 out of top 10 points of interest in this area
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.
La Cantera District
2 out of top 10 points of interest in this area
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Medical Center District Hotel Deals
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
CA $124
CA $146 total
Aug 12 - Aug 13
includes taxes & fees
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
CA $124
CA $147 total
Aug 22 - Aug 23
includes taxes & fees
8.8/10 Excellent! (1,006 reviews)
"The friendly staff"
Reviewed on Aug 10, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
Fully refundableReserve now, pay when you stay
CA $125
CA $148 total
Aug 16 - Aug 17
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Medical Center District vacation package cost?
Starting from just CA $762, a vacation package is your passport to low-priced travel. Create your own Medical Center District adventure by picking from our huge range of airfares, hotels and rental cars.
How do I get a cheap travel package to Medical Center District?
It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Center District vacation package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your vacation your own way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has a chance to travel and fulfill those vacation dreams.
Where should I stay in Medical Center District?
Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers.
What are the top hotels in Medical Center District?
Amazing, Contemporary, Beautiful and Fairfield Inn & Suites by Marriott San Antonio Medical Center are two of the most well-known hotels in Medical Center District. Why not take a look at the amenities and rates at each and then make up your mind?
How far in advance should I book my Medical Center District vacation?
It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure.
What does an Expedia Medical Center District travel package include?
Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Center District vacation.
What should I know before booking a Medical Center District travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between!
Can I choose my airline with a Medical Center District Expedia vacation package?
Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Center District trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Center District vacation package?
Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Center District vacation package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our Customer Service Portal. We're here to help you every step of the way.
Stay near popular Medical Center District attractions
USAA Corporate Office Headquarters
7.8/10 (7 reviews)
USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
Cinemark San Antonio 16
You can take time to visit Cinemark San Antonio 16 during your travels to San Antonio.
Things to do
San Antonio: Zoo Entry & Zoorassic Park Dinosaur Experience
CA $42
per adult
96% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
CA $53
per adult
98% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.